3oki | pdb_00003oki

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Template:STRUCTURE 3oki

File:3oki.png

Crystal structure of human FXR in complex with (2S)-2-[2-(4-chlorophenyl)-1H-benzimidazol-1-yl]-N,2-dicyclohexylethanamide

Template:ABSTRACT PUBMED 21134747

About this Structure

3oki is a 4 chain structure of Hormone with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Richter HG, Benson GM, Blum D, Chaput E, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S, Bleicher KH. Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes. Bioorg Med Chem Lett. 2011 Jan 1;21(1):191-4. Epub 2010 Nov 12. PMID:21134747 doi:10.1016/j.bmcl.2010.11.039

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