1k7l | pdb_00001k7l

Ligands:

544, YT3

Related:

1k74, 1fm6, 1fm9

Structural annotation:
Resources:	CATH : 1K7La00, 1K7Lc00, 1K7Le00, 1K7Lg00 UniProt : Q07869, Q66JL7

Functional annotation:
Cellular component:	nucleus
Biological process:	transcription regulation of transcription signal transduction regulation of transcription, DNA-dependent
Molecular function:	signal transducer activity transcription coactivator activity chromatin binding protein binding transcription regulator activity DNA binding nuclear hormone receptor binding

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

About this Structure

1k7l is a 8 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. Epub 2001 Nov 6. PMID:11698662 doi:10.1073/pnas.241410198
Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, McKee DD, Galardi CM, Plunket KD, Nolte RT, Parks DJ, Moore JT, Kliewer SA, Willson TM, Stimmel JB. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature. 2002 Feb 14;415(6873):813-7. PMID:11845213 doi:10.1038/415813a