2zhr | pdb_00002zhr

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File:2zhr.png


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2zhr, resolution 2.50Å (default scene)
Non-Standard Residues: 1OL
Gene: BACE1 (Homo sapiens)
Activity: Memapsin 2, with EC number 3.4.23.46
Related: 2zhs, 2zht, 2zhu, 2zhv
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of BACE1 in complex with OM99-2 at pH 5.0

Template:ABSTRACT PUBMED 18378702

About this Structure

2zhr is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Shimizu H, Tosaki A, Kaneko K, Hisano T, Sakurai T, Nukina N. Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production. Mol Cell Biol. 2008 Jun;28(11):3663-71. Epub 2008 Mar 31. PMID:18378702 doi:10.1128/MCB.02185-07

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