2vdo | pdb_00002vdo
From Proteopedia
INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO FIBRINOGEN GAMMA CHAIN PEPTIDE, HHLGGAKQAGDV
About this Structure
2vdo is a 5 chain structure of Fibrinogen with sequence from Homo sapiens and Mus musculus. The February 2011 RCSB PDB Molecule of the Month feature on Integrin by David Goodsell is 10.2210/rcsb_pdb/mom_2011_2. Full crystallographic information is available from OCA.
See Also
Reference
- Springer TA, Zhu J, Xiao T. Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3. J Cell Biol. 2008 Aug 25;182(4):791-800. Epub 2008 Aug 18. PMID:18710925 doi:jcb.200801146
- Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004 Nov 4;432(7013):59-67. Epub 2004 Sep 19. PMID:15378069 doi:https://dx.doi.org/10.1038/nature02976
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Integrin
- Mus musculus
- RCSB PDB Molecule of the Month
- Springer, T A.
- Xiao, T.
- Zhu, J.
- Antagonist
- Cell adhesion
- Cell adhesion-immune system complex
- Cleavage on pair of basic residue
- Disease mutation
- Fibrinogen binding
- Glycoprotein
- Host-virus interaction
- Membrane
- Phosphorylation
- Platelet integrin alphaiibbeta3
- Pyrrolidone carboxylic acid
- Receptor
- Transmembrane
