1au3 | pdb_00001au3
|
CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT PYRROLIDINONE INHIBITOR
Disease
Known disease associated with this structure: Pycnodysostosis OMIM:[601105]
About this Structure
1AU3 is a Single protein structure of sequence from Homo sapiens with PCM as ligand. Active as Cathepsin K, with EC number 3.4.22.38 Full crystallographic information is available from OCA.
Reference
Conformationally constrained 1,3-diamino ketones: a series of potent inhibitors of the cysteine protease cathepsin K., Marquis RW, Yamashita DS, Ru Y, LoCastro SM, Oh HJ, Erhard KF, DesJarlais RL, Head MS, Smith WW, Zhao B, Janson CA, Abdel-Meguid SS, Tomaszek TA, Levy MA, Veber DF, J Med Chem. 1998 Sep 10;41(19):3563-7. PMID:9733481
Page seeded by OCA on Thu Feb 21 11:48:22 2008
