1bpy | pdb_00001bpy

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Template:STRUCTURE 1bpy

File:1bpy.png

HUMAN DNA POLYMERASE BETA COMPLEXED WITH GAPPED DNA AND DDCTP

Template:ABSTRACT PUBMED 9287163

About this Structure

1bpy is a 4 chain structure of DNA polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sawaya MR, Prasad R, Wilson SH, Kraut J, Pelletier H. Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry. 1997 Sep 16;36(37):11205-15. PMID:9287163 doi:https://dx.doi.org/10.1021/bi9703812
  2. Jezewska MJ, Galletto R, Bujalowski W. Rat polymerase beta binds double-stranded DNA using exclusively the 8-kDa domain. Stoichiometries, intrinsic affinities, and cooperativities. Biochemistry. 2003 May 20;42(19):5955-70. PMID:12741854 doi:10.1021/bi030046f
  3. Rittenhouse RC, Apostoluk WK, Miller JH, Straatsma TP. Characterization of the active site of DNA polymerase beta by molecular dynamics and quantum chemical calculation. Proteins. 2003 Nov 15;53(3):667-82. PMID:14579358 doi:10.1002/prot.10451

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