2xpk | pdb_00002xpk

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Template:STRUCTURE 2xpk

File:2xpk.png

CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES

Template:ABSTRACT PUBMED 21095575

About this Structure

2xpk is a 2 chain structure of Beta-Hexosaminidase with sequence from Clostridium perfringens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Dorfmueller HC, Borodkin VS, Schimpl M, Zheng X, Kime R, Read KD, van Aalten DM. Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases. Chem Biol. 2010 Nov 24;17(11):1250-5. PMID:21095575 doi:10.1016/j.chembiol.2010.09.014

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