3l5d | pdb_00003l5d
From Proteopedia
Structure of BACE Bound to SCH723873
About this Structure
3l5d is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p
