2eb3 | pdb_00002eb3

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Template:STRUCTURE 2eb3

File:2eb3.png

Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP

Template:ABSTRACT PUBMED 22349823

About this Structure

2eb3 is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yoshikawa S, Kukimoto-Niino M, Parker L, Handa N, Terada T, Fujimoto T, Terazawa Y, Wakiyama M, Sato M, Sano S, Kobayashi T, Tanaka T, Chen L, Liu ZJ, Wang BC, Shirouzu M, Kawa S, Semba K, Yamamoto T, Yokoyama S. Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor. Oncogene. 2012 Feb 20. doi: 10.1038/onc.2012.21. PMID:22349823 doi:10.1038/onc.2012.21

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