2nru | pdb_00002nru

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File:2nru.png

Template:STRUCTURE 2nru

Crystal structure of IRAK-4

Template:ABSTRACT PUBMED 17161373

About this Structure

2nru is a 4 chain structure of Interleukin-1 receptor-associated kinase 4 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wang Z, Liu J, Sudom A, Ayres M, Li S, Wesche H, Powers JP, Walker NP. Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper. Structure. 2006 Dec;14(12):1835-44. PMID:17161373 doi:10.1016/j.str.2006.11.001
  2. Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121

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