3g49 | pdb_00003g49

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Template:STRUCTURE 3g49

File:3g49.png

N-(Pyridin-2-yl) Arylsulfonamide Inhibitors of 11b-Hydroxysteroid Dehydrogenase Type 1: Discovery of PF-915275

Template:ABSTRACT PUBMED 19473839

About this Structure

3g49 is a 4 chain structure of Hydroxysteroid dehydrogenase with sequence from Cavia porcellus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Siu M, Johnson TO, Wang Y, Nair SK, Taylor WD, Cripps SJ, Matthews JJ, Edwards MP, Pauly TA, Ermolieff J, Castro A, Hosea NA, LaPaglia A, Fanjul AN, Vogel JE. N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3493-7. Epub 2009 May 7. PMID:19473839 doi:10.1016/j.bmcl.2009.05.011

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