2jiv | pdb_00002jiv
From Proteopedia
CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION IN COMPEX WITH HKI-272
Template:ABSTRACT PUBMED 18227510
About this Structure
2jiv is a 2 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2070-5. Epub 2008 Jan 28. PMID:18227510
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Eck, M J.
- Greulich, H.
- Mengwasser, K E.
- Meyerson, M.
- Toms, A V.
- Wong, K K.
- Woo, M S.
- Yun, C H.
- Anti-oncogene
- Atp-binding
- Cell cycle
- Disease mutation
- Egfr
- Epidermal growth factor
- Hki-272
- Hki272
- Kinase
- Nucleotide-binding
- Phosphorylation
- Receptor
- T790m
- Transferase
- Transmembrane
- Tyrosine-protein kinase
