1kce | pdb_00001kce

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File:1kce.png

Template:STRUCTURE 1kce

E. COLI THYMIDYLATE SYNTHASE MUTANT E58Q IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

Template:ABSTRACT PUBMED 8973201

About this Structure

1kce is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sage CR, Rutenber EE, Stout TJ, Stroud RM. An essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58Q. Biochemistry. 1996 Dec 17;35(50):16270-81. PMID:8973201 doi:https://dx.doi.org/10.1021/bi961269r
  2. Stout TJ, Sage CR, Stroud RM. The additivity of substrate fragments in enzyme-ligand binding. Structure. 1998 Jul 15;6(7):839-48. PMID:9687366

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