2c5w | pdb_00002c5w

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Template:STRUCTURE 2c5w

File:2c5w.png

PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE

Template:ABSTRACT PUBMED 16316661

About this Structure

2c5w is a 2 chain structure of Penicillin-binding protein with sequence from Streptococcus pneumoniae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Contreras-Martel C, Job V, Di Guilmi AM, Vernet T, Dideberg O, Dessen A. Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae. J Mol Biol. 2006 Jan 27;355(4):684-96. Epub 2005 Nov 9. PMID:16316661 doi:10.1016/j.jmb.2005.10.030
  2. Job V, Di Guilmi AM, Martin L, Vernet T, Dideberg O, Dessen A. Structural studies of the transpeptidase domain of PBP1a from Streptococcus pneumoniae. Acta Crystallogr D Biol Crystallogr. 2003 Jun;59(Pt 6):1067-9. Epub 2003, May 23. PMID:12777776
  3. Di Guilmi AM, Mouz N, Andrieu JP, Hoskins J, Jaskunas SR, Gagnon J, Dideberg O, Vernet T. Identification, purification, and characterization of transpeptidase and glycosyltransferase domains of Streptococcus pneumoniae penicillin-binding protein 1a. J Bacteriol. 1998 Nov;180(21):5652-9. doi: 10.1128/JB.180.21.5652-5659.1998. PMID:9791115 doi:https://dx.doi.org/10.1128/JB.180.21.5652-5659.1998

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