3ui7 | pdb_00003ui7

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Template:STRUCTURE 3ui7

File:3ui7.png

Discovery of orally active pyrazoloquinoline as a potent PDE10 inhibitor for the management of schizophrenia

Template:ABSTRACT PUBMED 22142545

About this Structure

3ui7 is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R. Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia. Bioorg Med Chem Lett. 2011 Nov 16. PMID:22142545 doi:10.1016/j.bmcl.2011.11.023

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