2anq | pdb_00002anq

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File:2anq.png

Template:STRUCTURE 2anq

Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.

Template:ABSTRACT PUBMED 17125251

About this Structure

2anq is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v

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