3b2w | pdb_00003b2w

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Template:STRUCTURE 3b2w

File:3b2w.png

Crystal structure of pyrimidine amide 11 bound to Lck

Template:ABSTRACT PUBMED 18083554

About this Structure

3b2w is a 1 chain structure of Proto-oncogene tyrosine-protein kinase and Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Deak HL, Newcomb JR, Nunes JJ, Boucher C, Cheng AC, DiMauro EF, Epstein LF, Gallant P, Hodous BL, Huang X, Lee JH, Patel VF, Schneider S, Turci SM, Zhu X. N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1172-6. Epub 2007 Dec 5. PMID:18083554 doi:https://dx.doi.org/10.1016/j.bmcl.2007.11.123

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