2fib | pdb_00002fib

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Template:STRUCTURE 2fib

File:2fib.png

RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) COMPLEXED TO THE PEPTIDE GLY-PRO-ARG-PRO AT PH 6.0

Template:ABSTRACT PUBMED 9207064

About this Structure

2fib is a 2 chain structure of Fibrinogen with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Pratt KP, Cote HC, Chung DW, Stenkamp RE, Davie EW. The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7176-81. PMID:9207064
  2. Cote HC, Lord ST, Pratt KP. gamma-Chain dysfibrinogenemias: molecular structure-function relationships of naturally occurring mutations in the gamma chain of human fibrinogen. Blood. 1998 Oct 1;92(7):2195-212. PMID:9746756

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