2fdp | pdb_00002fdp
From Proteopedia
Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor
Template:ABSTRACT PUBMED 16451048
About this Structure
2fdp is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yang W, Lu W, Lu Y, Zhong M, Sun J, Thomas AE, Wilkinson JM, Fucini RV, Lam M, Randal M, Shi XP, Jacobs JW, McDowell RS, Gordon EM, Ballinger MD. Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1. J Med Chem. 2006 Feb 9;49(3):839-42. PMID:16451048 doi:10.1021/jm0509142
