3fv8 | pdb_00003fv8

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Template:STRUCTURE 3fv8

File:3fv8.png

JNK3 bound to piperazine amide inhibitor, SR2774.

Template:ABSTRACT PUBMED 19433357

About this Structure

3fv8 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Shin Y, Chen W, Habel J, Duckett D, Ling YY, Koenig M, He Y, Vojkovsky T, LoGrasso P, Kamenecka TM. Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3344-7. Epub 2009 Mar 26. PMID:19433357 doi:10.1016/j.bmcl.2009.03.086

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