1pq2 | pdb_00001pq2

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Template:STRUCTURE 1pq2

File:1pq2.png

Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

Template:ABSTRACT PUBMED 14676196

About this Structure

1pq2 is a 2 chain structure of Cytochrome P450 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF. Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15. PMID:14676196 doi:10.1074/jbc.M312516200
  2. Yano JK, Hsu MH, Griffin KJ, Stout CD, Johnson EF. Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. Nat Struct Mol Biol. 2005 Sep;12(9):822-3. Epub 2005 Aug 7. PMID:16086027 doi:https://dx.doi.org/10.1038/nsmb971
  3. Wu ZL, Podust LM, Guengerich FP. Expansion of substrate specificity of cytochrome P450 2A6 by random and site-directed mutagenesis. J Biol Chem. 2005 Dec 9;280(49):41090-100. Epub 2005 Oct 7. PMID:16215230 doi:10.1074/jbc.M508182200

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