3sff | pdb_00003sff

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File:3sff.png

Template:STRUCTURE 3sff

Crystal Structure of Human HDAC8 Inhibitor Complex, an Amino Acid Derived Inhibitor

Template:ABSTRACT PUBMED 21723733

About this Structure

3sff is a 1 chain structure of Histone deacetylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Whitehead L, Dobler MR, Radetich B, Zhu Y, Atadja PW, Claiborne T, Grob JE, McRiner A, Pancost MR, Patnaik A, Shao W, Shultz M, Tichkule R, Tommasi RA, Vash B, Wang P, Stams T. Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors. Bioorg Med Chem. 2011 Aug 1;19(15):4626-34. Epub 2011 Jun 15. PMID:21723733 doi:10.1016/j.bmc.2011.06.030

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