2gq2 | pdb_00002gq2

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Template:STRUCTURE 2gq2

File:2gq2.png

Mycobacterium tuberculosis ThyX-NADP complex

Template:ABSTRACT PUBMED 16730023

About this Structure

2gq2 is a 4 chain structure of Thymidylate synthase with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sampathkumar P, Turley S, Sibley CH, Hol WG. NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. J Mol Biol. 2006 Jun 30;360(1):1-6. Epub 2006 May 12. PMID:16730023 doi:10.1016/j.jmb.2006.04.061
  2. Sampathkumar P, Turley S, Ulmer JE, Rhie HG, Sibley CH, Hol WG. Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution. J Mol Biol. 2005 Oct 7;352(5):1091-104. PMID:16139296 doi:10.1016/j.jmb.2005.07.071

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