2itn | pdb_00002itn
From Proteopedia
CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AMP-PNP
Template:ABSTRACT PUBMED 17349580
About this Structure
2itn is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 2007 Mar;11(3):217-27. PMID:17349580 doi:https://dx.doi.org/10.1016/j.ccr.2006.12.017
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Boggon, T J.
- Eck, M J.
- Greulich, H.
- Li, Y.
- Meyerson, M.
- Woo, S.
- Yun, C H.
- Amp-pnp
- Anp
- Anti-oncogene
- Atp-binding
- Cell cycle
- Disease mutation
- Egfr
- Epidermal growth factor
- G719
- Glycoprotein
- Kinase
- Membrane
- Nucleotide-binding
- Phosphorylation
- Receptor
- Transferase
- Transmembrane
- Tyrosine-protein kinase
