3s7a | pdb_00003s7a

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Template:STRUCTURE 3s7a

File:3s7a.png

Human dihydrofolate reductase binary complex with PT684

Template:ABSTRACT PUBMED 21931219

About this Structure

3s7a is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cody V, Pace J, Nowak J. Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpter idine reveals an unusual binding mode. Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):875-80. Epub 2011, Sep 8. PMID:21931219 doi:10.1107/S0907444911030071

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