3qgn | pdb_00003qgn

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File:3qgn.png

Template:STRUCTURE 3qgn

The allosteric E*-E equilibrium is a key property of the trypsin fold

Template:ABSTRACT PUBMED 21707111

About this Structure

3qgn is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Niu W, Chen Z, Gandhi PS, Vogt AD, Pozzi N, Pelc LA, Zapata F, Di Cera E. Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease. Biochemistry. 2011 Jun 30. PMID:21707111 doi:10.1021/bi200878c
  2. Niu W, Chen Z, Bush-Pelc LA, Bah A, Gandhi PS, Di Cera E. Mutant N143P reveals how Na+ activates thrombin. J Biol Chem. 2009 Dec 25;284(52):36175-85. Epub 2009 Oct 21. PMID:19846563 doi:10.1074/jbc.M109.069500

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