2hu6 | pdb_00002hu6

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File:2hu6.png

Template:STRUCTURE 2hu6

Crystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitor

Template:ABSTRACT PUBMED 16899369

About this Structure

2hu6 is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Mannino C, Nievo M, Machetti F, Papakyriakou A, Calderone V, Fragai M, Guarna A. Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. Bioorg Med Chem. 2006 Nov 15;14(22):7392-403. Epub 2006 Aug 8. PMID:16899369 doi:10.1016/j.bmc.2006.07.028

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OCA

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