3k74 | pdb_00003k74

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Template:STRUCTURE 3k74

File:3k74.png

Disruption of protein dynamics by an allosteric effector antibody

Template:ABSTRACT PUBMED 021238460

About this Structure

3k74 is a 2 chain structure of Dihydrofolate reductase with sequence from Escherichia coli k-12 and Lama glama. Full crystallographic information is available from OCA.

See Also

Reference

  1. Oyen D, Srinivasan V, Steyaert J, Barlow JN. Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition. J Mol Biol. 2011 Mar 18;407(1):138-48. Epub 2011 Jan 14. PMID:21238460 doi:10.1016/j.jmb.2011.01.017

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OCA

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