3d08 | pdb_00003d08
From Proteopedia
Human p53 core domain with hot spot mutation R249S and second-site suppressor mutation H168R
Template:ABSTRACT PUBMED 18996393
About this Structure
3d08 is a 1 chain structure of P53 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Suad O, Rozenberg H, Brosh R, Diskin-Posner Y, Kessler N, Shimon LJ, Frolow F, Liran A, Rotter V, Shakked Z. Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations. J Mol Biol. 2009 Jan 9;385(1):249-65. Epub 2008 Oct 30. PMID:18996393 doi:10.1016/j.jmb.2008.10.063
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Frolow, F.
- Rozenberg, H.
- Shakked, Z.
- Shimon, L J.W.
- Suad, O.
- Activator
- Anti-oncogene
- Apoptosis
- Cell cycle
- Covalent protein-rna linkage
- Disease mutation
- Dna-binding
- Endoplasmic reticulum
- Glycoprotein
- Host-virus interaction
- Li-fraumeni syndrome
- Loop-sheet-helix motif
- Metal-binding
- Methylation
- Mutant protein
- Nucleus
- P53
- Phosphoprotein
- Transcription
- Transcription regulation
