1gjb | pdb_00001gjb
From Proteopedia
ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS
About this Structure
1gjb is a 2 chain structure of Urokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Katz BA, Sprengeler PA, Luong C, Verner E, Elrod K, Kirtley M, Janc J, Spencer JR, Breitenbucher JG, Hui H, McGee D, Allen D, Martelli A, Mackman RL. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem Biol. 2001 Nov;8(11):1107-21. PMID:11731301
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- U-plasminogen activator
- Allen, D.
- Breitenbucher, J G.
- Hui, H.
- Katz, B A.
- Luong, C.
- Mackman, R L.
- Martelli, A.
- McGee, D.
- Spencer, J R.
- Sprengeler, P A.
- Verner, E.
- Blood clotting
- H2o displacement
- Hydrolase
- Selectivity at s1
- Ser190/ala190 protease
- Structure-based drug design
- Tpa
- Upa
