1dpl | pdb_00001dpl

From Proteopedia
Revision as of 10:19, 21 February 2008 by OCA (talk | contribs)
Jump to navigationJump to search

A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE

File:1dpl.gif


1dpl, resolution 0.83Å

Drag the structure with the mouse to rotate

Overview

We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.

About this Structure

1DPL is a Protein complex structure of sequences from [1] with SPM and MG as ligands. Full crystallographic information is available from OCA.

Reference

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:10699842

Page seeded by OCA on Thu Feb 21 12:19:04 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA