3f3v | pdb_00003f3v

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Template:STRUCTURE 3f3v

File:3f3v.png

Kinase domain of cSrc in complex with inhibitor RL45 (Type II)

Template:ABSTRACT PUBMED 19462975

About this Structure

3f3v is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Getlik M, Grutter C, Simard JR, Kluter S, Rabiller M, Rode HB, Robubi A, Rauh D. Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem. 2009 Jul 9;52(13):3915-26. PMID:19462975 doi:10.1021/jm9002928

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