1imd | pdb_00001imd

Ligands:

MN, PO4

Gene:

CDNA (Homo sapiens)

Activity:

Inositol-phosphate phosphatase, with EC number 3.1.3.25

Structural annotation:
Resources:	CATH : 1Imda01, 1Imda02, 1Imdb02, 1Imdb01 InterPro : Ipr000760, Ipr000146 Pfam : PF00459 SCOP : d1imda_, d1imdb_ UniProt : P29218

Functional annotation:
Cellular component:	cytoplasm
Biological process:	signal transduction carbohydrate metabolic process phosphate metabolic process phosphatidylinositol biosynthetic process
Molecular function:	inositol-1(or 4)-monophosphatase activity metal ion binding lithium ion binding phosphoric ester hydrolase activity hydrolase activity magnesium ion binding inositol or phosphatidylinositol phosphatase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

About this Structure

1imd is a 2 chain structure of Inositol Monophosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Bone R, Frank L, Springer JP, Atack JR. Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis. Biochemistry. 1994 Aug 16;33(32):9468-76. PMID:8068621