2isp | pdb_00002isp

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Template:STRUCTURE 2isp

File:2isp.png

Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate

Template:ABSTRACT PUBMED 17209556

About this Structure

2isp is a 4 chain structure of DNA polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sucato CA, Upton TG, Kashemirov BA, Batra VK, Martinek V, Xiang Y, Beard WA, Pedersen LC, Wilson SH, McKenna CE, Florian J, Warshel A, Goodman MF. Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Biochemistry. 2007 Jan 16;46(2):461-71. PMID:17209556 doi:10.1021/bi061517b

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