2hd6 | pdb_00002hd6

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File:2hd6.png

Template:STRUCTURE 2hd6

Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide.

Template:ABSTRACT PUBMED 16942027

About this Structure

2hd6 is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. De Simone G, Vitale RM, Di Fiore A, Pedone C, Scozzafava A, Montero JL, Winum JY, Supuran CT. Carbonic anhydrase inhibitors: Hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX. J Med Chem. 2006 Sep 7;49(18):5544-51. PMID:16942027 doi:https://dx.doi.org/10.1021/jm060531j
  2. Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:https://dx.doi.org/10.1002/prot.340040406

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