2p4j | pdb_00002p4j
From Proteopedia
Crystal structure of beta-secretase bond to an inhibitor with Isophthalamide Derivatives at P2-P3
About this Structure
2p4j is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni SS, Xu X, Chang W, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands. J Med Chem. 2007 May 17;50(10):2399-407. Epub 2007 Apr 14. PMID:17432843 doi:10.1021/jm061338s
