1e26 | pdb_00001e26

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Template:STRUCTURE 1e26

File:1e26.png

DESIGN, SYNTHESIS AND X-RAY CRYSTAL STRUCTURE OF A POTENT DUAL INHIBITOR OF THYMIDYLATE SYNTHASE AND DIHYDROFOLATE REDUCTASE AS AN ANTITUMOR AGENT.

Template:ABSTRACT PUBMED 10194348

About this Structure

1e26 is a 1 chain structure of Dihydrofolate reductase with sequence from Pneumocystis carinii. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF. Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+. Biochemistry. 1999 Apr 6;38(14):4303-12. PMID:10194348 doi:10.1021/bi982728m

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OCA

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