1t7i | pdb_00001t7i

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File:1t7i.png

Template:STRUCTURE 1t7i

The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.

Template:ABSTRACT PUBMED 15771427

About this Structure

1t7i is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427 doi:10.1021/jm049560p

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