3edz | pdb_00003edz
From Proteopedia
Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
About this Structure
3edz is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X. Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5809-14. Epub 2008 Sep 13. PMID:18835710 doi:10.1016/j.bmcl.2008.09.045
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- ADAM 17 endopeptidase
- Homo sapiens
- Guo, Z.
- Kozlowski, J.
- Lavey, B.
- Lundell, D.
- Madison, V.
- Mazzola, R D.
- McKittrick, B.
- Neng-Yang, S.
- Niu, X.
- Orth, P.
- Sinning, L.
- Spitler, J.
- Sun, J.
- Zhou, G.
- Zhu, Z.
- Cleavage on pair of basic residue
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphoprotein
- Protease
- Sh3-binding
- Transmembrane
- Zn-endopeptidase
- Zymogen
