2xds | pdb_00002xds

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Template:STRUCTURE 2xds

File:2xds.png

STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND

Template:ABSTRACT PUBMED 20718493

About this Structure

2xds is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Murray CW, Carr MG, Callaghan O, Chessari G, Congreve M, Cowan S, Coyle JE, Downham R, Figueroa E, Frederickson M, Graham B, McMenamin R, O'Brien MA, Patel S, Phillips TR, Williams G, Woodhead AJ, Woolford AJ. Fragment-based drug discovery applied to hsp90. Discovery of two lead series with high ligand efficiency. J Med Chem. 2010 Aug 26;53(16):5942-55. PMID:20718493 doi:10.1021/jm100059d

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