2h4k | pdb_00002h4k

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Template:STRUCTURE 2h4k

File:2h4k.png

Crystal structure of PTP1B with a monocyclic thiophene inhibitor

Template:ABSTRACT PUBMED 16806920

About this Structure

2h4k is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wan ZK, Lee J, Xu W, Erbe DV, Joseph-McCarthy D, Follows BC, Zhang YL. Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: capturing interactions with Asp48. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4941-5. Epub 2006 Jun 27. PMID:16806920 doi:https://dx.doi.org/10.1016/j.bmcl.2006.06.051

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