3pre | pdb_00003pre

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File:3pre.png

Template:STRUCTURE 3pre

Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.

Template:ABSTRACT PUBMED 21269826

About this Structure

3pre is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Liu KK, Huang X, Bagrodia S, Chen JH, Greasley S, Cheng H, Sun S, Knighton D, Rodgers C, Rafidi K, Zou A, Xiao J, Yan S. Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1270-4. Epub 2010 Dec 10. PMID:21269826 doi:10.1016/j.bmcl.2010.12.026

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