3qpp | pdb_00003qpp

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Template:STRUCTURE 3qpp

File:3qpp.png

Structure of PDE10-inhibitor complex

Template:ABSTRACT PUBMED 21650160

About this Structure

3qpp is a 1 chain structure of Phosphodiesterase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Helal CJ, Kang Z, Hou X, Pandit J, Chappie TA, Humphrey JM, Marr ES, Fennell KF, Chenard LK, Fox C, Schmidt CJ, Williams RD, Chapin DS, Siuciak J, Lebel L, Menniti F, Cianfrogna J, Fonseca KR, Nelson FR, O'Connor R, Macdougall M, McDowell L, Liras S. Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J Med Chem. 2011 Jun 8. PMID:21650160 doi:10.1021/jm2001508

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