3mbl | pdb_00003mbl

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Template:STRUCTURE 3mbl

File:3mbl.png

Crystal Structure of the human mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgADP

Template:ABSTRACT PUBMED 20621728

About this Structure

3mbl is a 1 chain structure of Mitogen-activated protein kinase kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wallace MB, Adams ME, Kanouni T, Mol CD, Dougan DR, Feher VA, O'Connell SM, Shi L, Halkowycz P, Dong Q. Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4156-8. Epub 2010 May 20. PMID:20621728 doi:10.1016/j.bmcl.2010.05.058

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