1sa5 | pdb_00001sa5

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File:1sa5.png

Template:STRUCTURE 1sa5

Rat protein farnesyltransferase complexed with FPP and BMS-214662

Template:ABSTRACT PUBMED 15170324

About this Structure

1sa5 is a 2 chain structure of Farnesyltransferase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b

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