2iws | pdb_00002iws

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Template:STRUCTURE 2iws

File:2iws.png

RADICICOL ANALOGUES BOUND TO THE ATP SITE OF HSP90

Template:ABSTRACT PUBMED 17114002

About this Structure

2iws is a 1 chain structure of Heat Shock Proteins with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ. Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol. Chem Biol. 2006 Nov;13(11):1203-15. PMID:17114002 doi:10.1016/j.chembiol.2006.09.015

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