1zrb | pdb_00001zrb

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File:1zrb.png

Template:STRUCTURE 1zrb

Thrombin in complex with an azafluorenyl inhibitor 23b

Template:ABSTRACT PUBMED 15801822

About this Structure

1zrb is a 2 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Stauffer KJ, Williams PD, Selnick HG, Nantermet PG, Newton CL, Homnick CF, Zrada MM, Lewis SD, Lucas BJ, Krueger JA, Pietrak BL, Lyle EA, Singh R, Miller-Stein C, White RB, Wong B, Wallace AA, Sitko GR, Cook JJ, Holahan MA, Stranieri-Michener M, Leonard YM, Lynch JJ Jr, McMasters DR, Yan Y. 9-hydroxyazafluorenes and their use in thrombin inhibitors. J Med Chem. 2005 Apr 7;48(7):2282-93. PMID:15801822 doi:10.1021/jm049423s

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