3nw5 | pdb_00003nw5
From Proteopedia
Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)
About this Structure
3nw5 is a 1 chain structure of Hormone with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sampognaro AJ, Wittman MD, Carboni JM, Chang C, Greer AF, Hurlburt WW, Sack JS, Vyas DM. Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5027-30. Epub 2010 Jul 15. PMID:20675137 doi:10.1016/j.bmcl.2010.07.045
