3p2b | pdb_00003p2b

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Template:STRUCTURE 3p2b

File:3p2b.png

Crystal Structure of PI3K gamma with 3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-yl)phenol

Template:ABSTRACT PUBMED 21035331

About this Structure

3p2b is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Pecchi S, Renhowe PA, Taylor C, Kaufman S, Merritt H, Wiesmann M, Shoemaker KR, Knapp MS, Ornelas E, Hendrickson TF, Fantl W, Voliva CF. Identification and structure-activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6895-8. Epub 2010 Oct 13. PMID:21035331 doi:10.1016/j.bmcl.2010.10.021

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