3ixk | pdb_00003ixk

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File:3ixk.png

Template:STRUCTURE 3ixk

Potent beta-secretase 1 inhibitor

Template:ABSTRACT PUBMED 20036448

About this Structure

3ixk is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wangsell F, Gustafsson K, Kvarnstrom I, Borkakoti N, Edlund M, Jansson K, Lindberg J, Hallberg A, Rosenquist A, Samuelsson B. Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core. Eur J Med Chem. 2010 Mar;45(3):870-82. Epub 2009 Nov 12. PMID:20036448 doi:10.1016/j.ejmech.2009.11.013

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